iReceptor Plus aims to promote human immunological data storage, integration and controlled sharing for a wide range of clinical and scientific purposes, by developing an innovative platform to integrate distributed repositories of Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) data. iReceptor Plus will enable researchers around the world to share and analyze huge immunological datasets that have been sequenced and stored in databanks in multiple countries via one centralized web portal. This distributed, federated approach is central to the iReceptor Plus concept as it allows each institution to maintain control over their data and stay compliant with local legislation. The innovative platform will lower the barrier for academia, industry and clinical partners to access and analyze large AIRR-seq datasets and can thus lead to improved personalized medicine and immunotherapy in cancer, inflammatory and autoimmune diseases, allergies and infectious diseases
Timelex is the leading partner for all legal concerns in the iReceptor Plus project. As such, Timelex monitors any developments in applicable privacy, data protection and security regulations and provides feedback to the consortium on any resulting (architectural or design) requirements that should be respected. Moreover, Timelex is in charge of analyzing the legal lay of the land in regards the cross-border sharing of genomics data for scientific research purposes and providing recommendations for new regulatory regimes in this area to regulators. Timelex also supports the innovation management, exploitation and business planning working group by creating awareness of the legal, ethics, privacy and security challenges of iReceptor Plus that should be taken into account for sustainable implementation and successful usage of the iReceptor Plus platform. Further, Timelex is responsible for ensuring that the implementation of the project is in full compliance with ethical principles.